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Product Details
PA5-109727
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
Conjugate
Form
Liquid
Concentration
1.45 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855138
Product Specific Information
Immunogen sequence: MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFKFR IGKQEVIKGF EEGAAQLGPL SPLPICPHPC
Target Information
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; 126 kDa FKBP; calstabin 2; Calstabin-2; FK506 binding protein 1B, 12.6 kDa; FK506-binding protein 12.6; FK506-binding protein 1B; FKBP-12.6; FKBP-126; FKBP-1B; FKBP126; h-FKBP-12; Immunophilin FKBP12.6; Peptidyl-prolyl cis-trans isomerase FKBP1B; PPIase FKBP1B; Rotamase
Gene Aliases: 12.6kDa; AW494148; calstabin2; FKBP12.6; FKBP1B; FKBP1L; FKBP9; OTK4; PKBP1L; PPIase
UniProt ID: (Human) P68106, (Mouse) Q9Z2I2, (Rat) P97534
Entrez Gene ID: (Human) 2281, (Mouse) 14226, (Rat) 58950
protein peptidyl-prolyl isomerization
'de novo' protein folding
smooth muscle contraction
response to glucose
negative regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
neuronal action potential propagation
protein maturation by protein folding
insulin secretion
negative regulation of protein phosphatase type 2B activity
response to vitamin E
ion transmembrane transport
calcium-mediated signaling using intracellular calcium source
protein refolding
T cell proliferation
response to hydrogen peroxide
positive regulation of axon regeneration
negative regulation of release of sequestered calcium ion into cytosol
positive regulation of sequestering of calcium ion
regulation of cytosolic calcium ion concentration
response to redox state
regulation of ryanodine-sensitive calcium-release channel activity
negative regulation of ryanodine-sensitive calcium-release channel activity
chaperone-mediated protein folding
negative regulation of insulin secretion involved in cellular response to glucose stimulus
cell communication by electrical coupling involved in cardiac conduction
regulation of cardiac conduction
regulation of heart rate
protein folding
positive regulation of cytosolic calcium ion concentration
release of sequestered calcium ion into cytosol
response to organic substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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