Invitrogen

FKBP4 Polyclonal Antibody

FKBP4 Antibody in Immunocytochemistry (ICC/IF)

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FKBP4 Antibody (PA3-020) in ICC/IF

Immunofluorescent analysis of Heat Shock protein 56 (HSP56, green) in HeLa cells. Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA (Product # 37525) for 15 minutes at room temperature. Cells were probed without (left panel) or with (right panel) a HSP56 polyclonal antibody (Product # PA3-020) at a dilution of 1:100 for at least 1 hour at room temperature, washed with PBS, and incubated with DyLight 488 goat anti-rabbit IgG secondary antibody (Product # ... View More

FKBP4 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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产品信息

PA3-020

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

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免疫组化 (IHC)

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免疫组化（冰冻） (IHC (F))

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免疫细胞化学 (ICC/IF)

1:100

产品规格

种属反应

Human, Mouse, Non-human primate, Rabbit

已发表种属

Mouse, Non-human primate, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues C(441) K D E R N D V A G S Q S Q V E T E A(458) of rabbit Heat Shock Protein 56.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_325971

产品详细信息

PA3-020 detects heat shock protein 56 (HSP56), also known as FKBP4/FKBP52, from human, monkey, mouse and rabbit tissues.

PA3-020 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a prominent ~52 kDa band representing HSP56 HeLa cell lysate.

The PA3-020 immunogen is a synthetic peptide corresponding to residues C(441) K D E R N D V A G S Q S Q V E T E A(458) of rabbit Heat Shock Protein 56.

Reconstitute in 100 µL PBS to create a stock of 1 mg/mL.

靶标信息

The function of this protein remains unknown.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform.

Molecular endocrinology (Baltimore, Md.)

Yang Z,Wolf IM,Chen H,Periyasamy S,Chen Z,Yong W,Shi S,Zhao W,Xu J,Srivastava A,Sánchez ER,Shou W

PA3-020 was used in western blot to study the role of FKBP52 in progesterone receptor action.

Wed Nov 01 00:00:00 UTC 2006

Protection against ischemic brain damage in rats by immunophilin ligand GPI-1046.

Journal of neuroscience research

Li F,Omori N,Hayashi T,Jin G,Sato K,Nagano I,Shoji M,Abe K

PA3-020 was used in immunohistochemistry to evaluate the protective effect of immunophilin ligand GPI-1046 against ischemic brain damage in rats

Sat May 01 00:00:00 UTC 2004

Early decrease of the immunophilin FKBP 52 in the spinal cord of a transgenic model for amyotrophic lateral sclerosis.

Brain research

Manabe Y,Warita H,Murakami T,Shiote M,Hayashi T,Omori N,Nagano I,Shoji M,Abe K

PA3-020 was used in immunohistochemistry to investigate the effect of the downregulation of FKBP-52 on the pathogenesis of amyotrophic lateral sclerosis

Fri May 10 00:00:00 UTC 2002

Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent.

Molecular and cellular biology

Smith DF,Whitesell L,Nair SC,Chen S,Prapapanich V,Rimerman RA

PA3-020 was used in western blot to investigate the assembly pathway of progesterone receptor complexes

Fri Dec 01 00:00:00 UTC 1995

生物信息学

蛋白别名: 51 kDa FK506-binding protein; 52 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; FK506 binding protein 4, 59kDa; FK506-binding protein 4; FK506-binding protein 4 (59kD); FKBP-4; FKBP51; FKBP52 protein; FKBP59; HBI; HSP binding immunophilin; HSP-binding immunophilin; hsp90 binding protein; Immunophilin FKBP52; p59; Peptidyl-prolyl cis-trans isomerase FKBP4; Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed; peptidylprolyl cis-trans isomerase; PPIase FKBP4; Rotamase; T-cell FK506-binding protein, 59kD

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基因别名: 59kDa; AL022792; AW208983; FKBP-4; FKBP-52; FKBP4; FKBP51; FKBP52; FKBP59; FKPB52; HBI; Hsp56; p52; P59; PPIase

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UniProt ID: (Rabbit) P27124, (Human) Q02790, (Mouse) P30416

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Entrez Gene ID: (Rabbit) 100009148, (Human) 2288, (Mouse) 14228

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功能