Abnova

FLCN Polyclonal Antibody, MaxPab™

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FLCN Antibody in Western Blot (WB)

FLCN Antibody in Western Blot (WB)

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FLCN Antibody (H00201163-B01P) in WB

Western Blot analysis of FLCN expression in transfected 293T cell line by FLCN MaxPab polyclonal antibody. Lane 1: FLCN transfected lysate(37.62 KDa). Lane 2: Non-transfected lysate. .

FLCN Antibody in Western Blot (WB)

Product Image Gallery

FLCN Antibody in Western Blot (WB) — Western Blot analysis of FLCN expression in transfected 293T cell line by FLCN MaxPab polyclonal antibody. Lane 1: FLCN transfected lysate(37.62 KDa). Lane 2: Non-transfected lysate. .

产品信息

H00201163-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

FLCN (NP_653207.1, 1 a.a. approximately 342 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5-1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MNAIVALCHF CELHGPRTLF CTEVLHAPLP QGDGNEDSPG QGEQAEEEEG GIQMNSRMRA HSPAEGASVE SSSPGPKKSD MCEGCRSLAA GHPGYISHDK ETSIKYVSHQ HPSHPQLFSI VRQACVRSLS CEVCPGREGP IFFGDEQHGF VFSHTFFIKD SLARGFQRWY SIITIMMDRI YLINSWPFLL GKVRGIIDEL QGKALKVFEA EQFGCPQRAQ RMNTAFTPFL HQRNGNAARS LTSLTSDDNL WACLHTSFAW LLKACGSRLT EKLLEGAPTE DTLVQMEKLA GEAGVLLPGP WPGWPWGGTS CLLSWQESLR EGNAALNQPR TSLREAHPPI SV

靶标信息

This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Folliculin

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基因别名: BHD; FLCL; FLCN

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UniProt ID: (Human) Q8NFG4

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Entrez Gene ID: (Human) 201163

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guanyl-nucleotide exchange factor activity protein binding protein complex binding

negative regulation of transcription from RNA polymerase II promoter in utero embryonic development regulation of protein phosphorylation positive regulation of protein phosphorylation cell-cell junction assembly positive regulation of autophagy negative regulation of gene expression negative regulation of mitochondrion organization hemopoiesis negative regulation of cell growth negative regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway TOR signaling regulation of TOR signaling negative regulation of TOR signaling positive regulation of TOR signaling regulation of cytokinesis negative regulation of Rho protein signal transduction regulation of histone acetylation positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of cell adhesion positive regulation of transcription from RNA polymerase II promoter negative regulation of protein kinase B signaling negative regulation of ERK1 and ERK2 cascade negative regulation of protein localization to nucleus negative regulation of cell proliferation involved in kidney development negative regulation of energy homeostasis regulation of pro-B cell differentiation negative regulation of ATP biosynthetic process