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NeoBiotechnologies
FLI1 (Ewing's Sarcoma and Endothelial Marker) Recombinant Mouse Monoclonal Antibody (rFLI1/9614)
产品信息
2313-MSM15-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rFLI1/9614
抗原
Recombinant fragment (around aa200-400) of human FLI1 protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Positive Control:Human tonsil, Ewing's sarcoma (EWS) or angiosarcoma. THP1 or Raji cells.
Cellular Location: Nucleus.
靶标信息
ETS-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes ETS-1, ETS-2, ERG-1, ERG-2, ELK, E74, FLI-1, PU. 1 and PEA3. Members of the ETS gene family exhibit varied pattern of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ewing sarcoma breakpoint region 2; Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; Proto-oncogene Fli-1; Transcription factor ERGB
基因别名: EWSR2; FLI1; SIC-1
UniProt ID: (Human) Q01543
Entrez Gene ID: (Human) 2313
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
winged helix/forkhead transcription factor
