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Immunogen sequence: KSDLRRHNIN IGITNVDVKA IPADSPTDQE PKTVMLSKQS ESAI
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 50%.
This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Choline/ethanolamine transporter FLVCR1; Feline leukemia virus subgroup C receptor; Feline leukemia virus subgroup C receptor-related protein 1; FLVCR protein; Heme transporter FLVCR1
Gene Aliases: AXPC1; FLVCR; FLVCR1; MFSD7B; PCA; PCARP
UniProt ID: (Human) Q9Y5Y0
Entrez Gene ID: (Human) 28982
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