Invitrogen

FMN2 Polyclonal Antibody

FMN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FMN2 Antibody (PA5-23251) in IHC (P)

Immunohistochemical analysis of FMN2 in Tissue section of human brain. Samples were incubated in FMN2 polyclonal antibody (Product # PA5-23251) using a dilution of 1:300. The signal was developed using HRP-labeled secondary and DAB reagent which followed counterstaining of nuclei with hematoxylin. This FMN2 antibody generated a nuclear and cytoplasmic staining primarily in the glial cells.

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产品信息

PA5-23251

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:4,000

免疫组化（石蜡） (IHC (P))

1:300-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to amino acids 657-688 of human FMN2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2540776

靶标信息

FMN2, a novel formin homology protein of the cappuccino subfamily, is highly conserved between evolutionarily diverse vertebrates. FMN2 bears a high degree of similarity to formin-1 which is the founding member of formin homology proteins. FMN2 plays a crucial role in maintenance of the meiotic spindle. The protein is widely expressed in human fetal brain, adult whole brain, hypothalamus, retina, pancreatic islet and germinal-center B cells. Pathological role of the protein is identified in various tumors like parathyloid tumor, glioblastoma, retinoblastoma and chondrosarcoma. FMN2 mutations are often a cause of unexplained infertility in women. The gene encoding for human FMN2 is localized in the chromosomal region 1q43.

仅用于科研。不用于诊断过程。未经明确授权不得转售。