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产品信息
PA5-52516
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641679
产品详细信息
Immunogen sequence: LHYLVKVIAE KYPQLTGFHS DLHFLDKAGS VSLDSVLADV RSLQRGLELT QREFVRQDDC MVLKEFLRAN SPTMDKLLAD SKTAQEAFES VVEYFGENPK TTSPGLFFSL FS
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
靶标信息
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
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生物信息学
蛋白别名: CLL-associated antigen KW-13; formin-like 1; Formin-like protein 1; Leukocyte formin
基因别名: C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; FRL1; KW-13
UniProt ID: (Human) O95466
Entrez Gene ID: (Human) 752
