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FIGURE: 1 / 1
FMO2 Antibody (PA5-109732) in WB
Western blot analysis of FMO2 in extracts of various cell lines. Samples were incubated with FMO2 Polyclonal antibody (Product # PA5-109732) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-109732
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 210-470 of human FMO2 (NP_001451.2).
Conjugate
Form
Liquid
Concentration
0.66 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855143
Product Specific Information
Immunogen sequence: VFISTRHGTW VMSRISEDGY PWDSVFHTRF RSMLRNVLPR TAVKWMIEQQ MNRWFNHENY GLEPQNKYIM KEPVLNDDVP SRLLCGAIKV KSTVKELTET SAIFEDGTVE ENIDVIIFAT GYSFSFPFLE DSLVKVENNM VSLYKYIFPA HLDKSTLACI GLIQPLGSIF PTAELQARWV TRVFKGLCSL PSERTMMMDI IKRNEKRIDL FGESQSQTLQ TNYVDYLDEL ALEIGAKPDF CSLLFKDPKL AVRLYFGPCN S
Target Information
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dimethylaniline oxidase 2; flavin containing monooxygenase 2 (non-functional); Flavin-containing monooxygenase 2; FMO 1B1; FMO 2; FMO, pulmonary; Pulmonary flavin-containing monooxygenase 2
Gene Aliases: FMO1B1; FMO2
UniProt ID: (Human) Q99518
Entrez Gene ID: (Human) 2327
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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