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产品信息
3169-MSM5-P1ABX
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
FOXA1, 1515
抗原
Recombinant human FOXA1 protein fragment (aa372-472)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
This antibody does not react with Rat.
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ci-fkh; fkd7; fkh; Forkhead box protein A1; forkhead-7; FoxA4a; Hepatocyte nuclear factor 3-alpha; HNF-3-alpha; HNF-3A; HNF3-alpha; HNF3alpha; MGC33105; MGC52590; MGC75967; pintallavis; TCF-3A; tFoxA1; Transcription factor 3A; xfkh1; xfkh2
基因别名: FOXA1; HNF3A; TCF3A
UniProt ID: (Human) P55317
Entrez Gene ID: (Human) 3169
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
protein domain specific binding
sequence-specific DNA binding
transcription regulatory region DNA binding
winged helix/forkhead transcription factor
negative regulation of transcription from RNA polymerase II promoter
chromatin remodeling
transcription from RNA polymerase II promoter
Notch signaling pathway
negative regulation of epithelial to mesenchymal transition
covalent chromatin modification
dorsal/ventral neural tube patterning
response to estradiol
positive regulation of intracellular estrogen receptor signaling pathway
hormone metabolic process
glucose homeostasis
positive regulation of neuron differentiation
positive regulation of smoothened signaling pathway
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
neuron fate specification
positive regulation of sequence-specific DNA binding transcription factor activity
epithelial tube branching involved in lung morphogenesis
lung epithelial cell differentiation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
epithelial-mesenchymal signaling involved in prostate gland development
prostate gland epithelium morphogenesis
prostate gland stromal morphogenesis
epithelial cell maturation involved in prostate gland development
alveolar secondary septum development
dopaminergic neuron differentiation
respiratory basal cell differentiation
positive regulation of cell-cell adhesion mediated by cadherin
