Bethyl Laboratories

FOXC2 Recombinant Rabbit Monoclonal Antibody (BLR184J)

查看其他19个FOXC2抗体

产品信息

A700-184

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

免疫细胞化学 (ICC/IF)

1:100-1:500

-

免疫沉淀 (IP)

20 µL/mg of lysate

-

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

BLR184J

抗原

Peptide representing a region between residue 350 and 400 of Human Forkhead box protein C2.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

250 µg/mL

纯化类型

purified

保存液

BBS, pH 8.2, with 0.1% BSA

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunocytochemistry: Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

靶标信息

Forkhead box protein C2 (FOXC2) is a transciptional activator and is characterized by a distinct DNA-binding forkhead domain. FOXC2 may be involved in the formation of special mesenchymal tissues. Mutations affecting the gene can cause lymphedema-distichiasis (LYD).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BF-3; Brain factor 3; forkhead box C2 (MFH-1, mesenchyme forkhead 1); Forkhead box protein C2; forkhead homolog 14; forkhead, Drosophila, homolog-like 14; Forkhead-related protein FKHL14; Mesenchyme fork head protein 1; mesenchyme forkhead 1; MFH-1 protein; MFH-1,mesenchyme forkhead 1; Transcription factor FKH-14

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基因别名: Fkh14; FKHL14; FOXC2; Hfhbf3; LD; MFH-1; MFH1

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UniProt ID: (Human) Q99958, (Mouse) Q61850

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Entrez Gene ID: (Human) 2303, (Mouse) 14234

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transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding chromatin DNA binding identical protein binding sequence-specific DNA binding transcription regulatory region DNA binding DNA binding winged helix/forkhead transcription factor

negative regulation of transcription from RNA polymerase II promoter ossification patterning of blood vessels metanephros development ureteric bud development somitogenesis lymphangiogenesis blood vessel remodeling transcription from RNA polymerase II promoter Notch signaling pathway mesoderm development heart development insulin receptor signaling pathway response to hormone positive regulation of endothelial cell migration neural crest cell development collagen fibril organization positive regulation of cell adhesion mediated by integrin embryonic heart tube development positive regulation of vascular wound healing camera-type eye development positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of organ growth vascular endothelial growth factor receptor signaling pathway paraxial mesodermal cell fate commitment embryonic viscerocranium morphogenesis artery morphogenesis regulation of blood vessel size ventricular cardiac muscle tissue morphogenesis cardiac muscle cell proliferation glomerular endothelium development glomerular visceral epithelial cell differentiation glomerular mesangial cell development positive regulation of cell migration involved in sprouting angiogenesis negative regulation of apoptotic process involved in outflow tract morphogenesis skeletal system development blood vessel development kidney development lymph vessel development heart morphogenesis transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter multicellular organism development cell proliferation positive regulation of integrin activation paraxial mesoderm formation embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis