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产品信息
PA5-40422
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human FOXE1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2610524
产品详细信息
Peptide sequence: APATTTGYQP AGCTGARPAN PSAYAAAYAG PDGAYPQGAG SAIFAAAGRL
Sequence homology: Cow: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
靶标信息
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
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生物信息学
蛋白别名: forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TTF-2
基因别名: FKHL15; FOXE1; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2
UniProt ID: (Human) O00358
Entrez Gene ID: (Human) 2304
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
anatomical structure morphogenesis
cell migration
thyroid gland development
hair follicle morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
thymus development
embryonic organ morphogenesis
hard palate development
soft palate development
pharynx development
