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产品信息
PA5-99311
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FOXE1(Accession O00358), corresponding to amino acid residues M1-G41.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2818244
产品详细信息
Antibody detects endogenous levels of total TTF2.
靶标信息
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: forkhead box E1 (thyroid transcription factor 2); forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; forkhead, drosophila, homolog-like 15; Forkhead-related protein FKHL15; HFKH4; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TTF-2
基因别名: FKHL15; FOXE1; FOXE2; HFKH4; HFKL5; NMTC4; TITF2; TTF-2; TTF2
UniProt ID: (Human) O00358, (Mouse) Q8R2I0
Entrez Gene ID: (Human) 2304, (Rat) 192274, (Mouse) 110805
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
anatomical structure morphogenesis
cell migration
thyroid gland development
hair follicle morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
thymus development
embryonic organ morphogenesis
hard palate development
soft palate development
pharynx development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell differentiation
