Invitrogen

FOXN1 Polyclonal Antibody

FOXN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

FOXN1 Antibody (PA5-18191) in IHC (P)

Immunohistochemistry analysis of FOXN1 in human thymus, medulla. Samples were incubated with FOXN1 polyclonal antibody (Product # PA5-18191) using a dilution of 20 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Image Gallery

产品信息

PA5-18191

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

4-6 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (SVYLSPSSKPVALA) corresponding to the C-terminus amino acids of FOXN1 (aa 635-648).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_10977719

产品详细信息

This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

靶标信息

FOXN1 is a 648 amino acid protein belonging to the winged helix/forkhead family It contains 1 fork-head DNA-binding domain and is a transcriptional regulator involved in development. FOXN1 is involved in directing lineage choices of multi-potential progenitor epithelial cells and controls important regulating genes of lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicles and nail apparatus and its defects lead to T-cell immunodeficiency congenital alopecia, nail dystrophy, macroscopic nudity and an inborn dysgenesis of the thymus.

仅用于科研。不用于诊断过程。未经明确授权不得转售。