Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
FOXN1 Antibody (PA5-21618) in WB
Western Blot analysis of FOXN1 was performed by separating 50 µg of Various tissue extracts by 7.5% SDS-PAGE. Proteins were transferred to a membrane and probed with a FOXN1 Polyclonal Antibody (Product # PA5-21618) at a dilution of 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
产品信息
PA5-21618
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 585 and 648 of FOXN1 (Uniprot ID#O15353)
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152532
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, A549, H1299, HCT116.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
FOXN1 is a 648 amino acid protein belonging to the winged helix/forkhead family It contains 1 fork-head DNA-binding domain and is a transcriptional regulator involved in development. FOXN1 is involved in directing lineage choices of multi-potential progenitor epithelial cells and controls important regulating genes of lympho-epithelial interactions. It modulates keratinocyte differentiation in hair follicles and nail apparatus and its defects lead to T-cell immunodeficiency congenital alopecia, nail dystrophy, macroscopic nudity and an inborn dysgenesis of the thymus.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Forkhead box protein N1; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/forkhead homolog 11; JTK1; Rowett nude; winged helix nude; winged-helix nude; Winged-helix transcription factor nude
基因别名: D11Bhm185e; Fkh19; FKHL20; FOXN1; HFH-11; Hfh11; nu; nude; Rnu; RONU; WHN
UniProt ID: (Human) O15353, (Mouse) Q61575
Entrez Gene ID: (Human) 8456, (Rat) 287469, (Mouse) 15218
hair follicle development
lymphocyte homeostasis
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell proliferation
epidermis development
regulation of gene expression
keratinocyte differentiation
regulation of T cell differentiation in thymus
nail development
thymus development
epithelial cell proliferation
T cell lineage commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
hemopoiesis
cell differentiation
T cell homeostasis
blood vessel morphogenesis
positive regulation of hair follicle development
lymphoid lineage cell migration into thymus
thymus epithelium morphogenesis
regulation of positive thymic T cell selection
defense response
organ morphogenesis
positive regulation of epithelial cell differentiation
