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产品信息
PA5-49682
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around aa.7~11(S-E-T-I-R) derived from Human FOXP4.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2635135
产品详细信息
The antibody detects endogenous level of total FOXP4 protein.
靶标信息
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ40908; FLJ44184; fork head-related protein like A; Fork head-related protein-like A; Forkhead box protein P4; foxp4; mFKHLA; OTTHUMP00000043536; winged-helix repressor FOXP4
基因别名: 1200010K03Rik; 2310007G05Rik; FKHLA; FOXP4; hFKHLA; mFKHLA
UniProt ID: (Human) Q8IVH2, (Mouse) Q9DBY0
Entrez Gene ID: (Human) 116113, (Mouse) 74123, (Rat) 363185
RNA polymerase II transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
metal ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
protein heterodimerization activity
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
heart development
embryonic foregut morphogenesis
lung secretory cell differentiation
regulation of lung goblet cell differentiation
negative regulation of lung goblet cell differentiation
regulation of transcription from RNA polymerase II promoter
