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Positive test controls include: SH-SY5Y, HeLa, HepG2, MCF7, Mouse kidney, OVCAR8, Rat lung, Rat spleen. The target is usually found in the following locations: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein.
Immunogen sequence: KEWKKEASKV RQYEVTWGID QFGPPMIIHF RVQYYVENGR LISDRAARYY YYWHLRKQVL HSQCVLREEA YFLLAAFALQ ADLGNFKRNK HYGKYFEPEA YF
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 4.1 ezrin radixin moesin (FERM)-containing protein; expanded homolog; FERM domain-containing protein 163SCII; FERM domain-containing protein 6; FERM-domain-containing protein 163SCII; MGC17921; Willin
基因别名: 2610019M19Rik; 4930488L10Rik; AW212977; c14_5320; C14orf31; EX1; FRMD6; Willin
UniProt ID: (Human) Q96NE9, (Mouse) Q8C0V9
Entrez Gene ID: (Human) 122786, (Rat) 257646, (Mouse) 319710