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FRZB Antibody (PA5-47793) in IHC (F)
Immunohistochemical analysis of FRZB in immersion fixed frozen sections of mouse embryo (E15). Samples were incubated in FRZB polyclonal antibody (Product # PA5-47793) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to dorsal root ganglia.
Product Details
PA5-47793
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse sFRP-3 Ala33-Ser323
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608225
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FREOS1; Frezzled; Fritz; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; sFRP-3; SFRP3frezzled
Gene Aliases: Fiz; Fre; frezzled; fritz; Frp; Frzb; frzb-1; Frzb1; Sfrp3
UniProt ID: (Mouse) P97401
Entrez Gene ID: (Mouse) 20378
multicellular organism development
negative regulation of cell proliferation
negative regulation of cell development
Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
inner ear morphogenesis
positive regulation of apoptotic process
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
canonical Wnt signaling pathway
negative regulation of cartilage development
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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