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FRZB Antibody (PA5-47793) in IHC (F)
Immunohistochemical analysis of FRZB in immersion fixed frozen sections of mouse embryo (E15). Samples were incubated in FRZB polyclonal antibody (Product # PA5-47793) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to dorsal root ganglia.
产品信息
PA5-47793
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse sFRP-3 Ala33-Ser323
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2608225
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FREOS1; Frezzled; Fritz; Frizzled-related protein 1; FrzB-1; FRZB1sFRP-3; Secreted frizzled-related protein 3; secreted frizzled-related sequence protein 3; sFRP-3; SFRP3frezzled
基因别名: Fiz; Fre; frezzled; fritz; Frp; Frzb; frzb-1; Frzb1; Sfrp3
UniProt ID: (Mouse) P97401
Entrez Gene ID: (Mouse) 20378
multicellular organism development
negative regulation of cell proliferation
negative regulation of cell development
Wnt signaling pathway
cell differentiation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
non-canonical Wnt signaling pathway
inner ear morphogenesis
positive regulation of apoptotic process
positive regulation of fat cell differentiation
convergent extension involved in organogenesis
canonical Wnt signaling pathway
negative regulation of cartilage development
negative regulation of hepatocyte differentiation
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
