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Immunogen sequence: AIHPLLSKMT LNFGTEMKRK ALFPHHVIPD SFLKRHEECC VFFHKYQLET ISENIRLFEC MGKAEQEKLN NLRDCAIQYF MQKFQLKHLS RNNWLVK
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 81%.
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adrift homolog; Cap methyltransferase 2; Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; Cap2 2'O-ribose methyltransferase 2; FtsJ methyltransferase domain containing 1; FtsJ methyltransferase domain-containing protein 1; HMTr2; Protein adrift homolog
基因别名: AFT; CMTR2; FTSJD1; HMTr2; MTr2
UniProt ID: (Human) Q8IYT2
Entrez Gene ID: (Human) 55783