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Peptide sequence: YRLEEMEKIF VRLEMKIIKG SSGTPKLSYT GRDDRHFVPM GLYIVRTVNE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cap methyltransferase 1; Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; Cap1 2'O-ribose methyltransferase 1; FtsJ methyltransferase domain containing 2; FtsJ methyltransferase domain-containing protein 2; Interferon-stimulated gene 95 kDa protein; ISG95; MTr1; S-adenosyl-L-methionine-dependent methyltransferase FTSJD2
基因别名: CMTR1; FTSJD2; hMTr1; KIAA0082; MTR1
UniProt ID: (Human) Q8N1G2
Entrez Gene ID: (Human) 23070