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FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3; 4-fucosyltransferase; 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase; alpha-(1,3/1,4)-fucosyltransferase; Alpha-3-fucosyltransferase FUT3; Blood group Lewis alpha-4-fucosyltransferase; Fuc-TV; Fucosyltransferase 3; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group); Fucosyltransferase III; FucT-III; FucT-V; Lewis FT; Lewis Y
基因别名: CD174; FT3B; FucT-III; FUT3; LE; Les
UniProt ID: (Human) P21217
Entrez Gene ID: (Human) 2525