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FUT8 Antibody (PA5-88872) in WB
Western blot analysis of FUT8 in extracts of various cell lines. Samples were incubated with FUT8 Polyclonal antibody (Product # PA5-88872) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88872
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 376-575 of human FUT8 (NP_8353671)
偶联物
形式
Liquid
浓度
0.85 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805185
产品详细信息
Immunogen sequence: FHPIEEYMVH VEEHFQLLAR RMQVDKKRVY LATDDPSLLK EAKTKYPNYE FISDNSISWS AGLHNRYTEN SLRGVILDIH FLSQADFLVC TFSSQVCRVA YEIMQTLHPD ASANFHSLDD IYYFGGQNAH NQIAIYAHQP RTADEIPMEP GDIIGVAGNH WDGYSKGVNR KLGRTGLYPS YKVREKIETV KYPTYPEAEK; Positive Samples: A-549, Mouse kidney; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
靶标信息
Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha (1,6) fucosyltransferase; Alpha-(1,6)-fucosyltransferase; alpha-1,6-fucosyltransferase; Alpha1-6FucT; EC 2.4.1.68; Fucosyltransferase 8; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; MGC26465
基因别名: FUT8
UniProt ID: (Human) Q9BYC5, (Mouse) Q9WTS2
Entrez Gene ID: (Human) 2530, (Mouse) 53618
in utero embryonic development
protein N-linked glycosylation
N-glycan processing
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
respiratory gaseous exchange
oligosaccharide biosynthetic process
regulation of gene expression
cell migration
protein N-linked glycosylation via asparagine
protein glycosylation in Golgi
N-glycan fucosylation
L-fucose catabolic process
receptor metabolic process
GDP-L-fucose metabolic process
regulation of cellular response to oxidative stress
fucosylation
