Invitrogen

FUZ Polyclonal Antibody

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FUZ Antibody (PA5-23209) in WB

Western blot analysis of FUZ in human lung lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse lung and 4) rat lung. Samples were incubated in FUZ polyclonal antibody (Product # PA5-23209) using a dilution of 0 µg/mL, 2.0 µg/mL and 6.0 µg/mL respectively.

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产品信息

PA5-23209

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2-6 µg/mL

免疫组化（石蜡） (IHC (P))

15 µg/mL

产品规格

种属反应

Rat, Human, Mouse, Non-human primate

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to amino acids 338-382 of human FUZ

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein G

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2540735

靶标信息

FUZ is the human homolog of Drosophila fy protein and belongs to the fuzzy family. The fy gene of Drosophila encodes a novel four-pass transmembrane protein that plays two roles in the development of hairs on the Drosophila wing. The first is to specify the correct orientation of the hair by restricting its initiation to the distal vertex of the cell. The second role is to permit the development of just a single cell hair by maintaining the integrity of the F-actin and microtubule arrays that are required for hair development. In humans, the protein is involved in cytoskeleton function and cell polarity in epithelial cells. The human fuz gene is localized on chromosome 19q13.33.

仅用于科研。不用于诊断过程。未经明确授权不得转售。