Abnova

FXN Monoclonal Antibody (3G9)

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抗体检测数据 (2)

FXN Antibody in Western Blot (WB)

FXN Antibody in Western Blot (WB)

图: 1 / 2

FXN Antibody (H00002395-M03) in WB

Western blot analysis of FXN over-expressed 293 cell line, cotransfected with FXN Validated Chimera RNAi (Cat # H00002395-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FXN monoclonal antibody (M03), clone 3G9 (Cat # H00002395-M03). GAPDH ( 36.1 kDa ) used as specificity and loading control.

FXN Antibody in Western Blot (WB)

FXN Antibody in Western Blot (WB)

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FXN Antibody in Western Blot (WB) — Western blot analysis of FXN over-expressed 293 cell line, cotransfected with FXN Validated Chimera RNAi (Cat # H00002395-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with FXN monoclonal antibody (M03), clone 3G9 (Cat # H00002395-M03). GAPDH ( 36.1 kDa ) used as specificity and loading control.

FXN Antibody in Western Blot (WB) — Western Blot analysis of FXN expression in transfected 293T cell line by FXN monoclonal antibody (M03), clone 3G9.

Lane 1: FXN transfected lysate(23.1 KDa).
Lane 2: Non-transfected lysate.

产品信息

H00002395-M03

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

3G9

抗原

FXN (AAH48097.1, 91 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

See Label

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Sequence of this protein is as follows: DETTYERLAE ETLDSLAEFF EDLADKPYTF EDYDVSFGSG VLTVKLGGDL GTYVINKQTP NKQIWLSSPS SGPKRYDWTG KNWVYSHDGV SLHELLAAEL TKALKTKLDL

靶标信息

FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Frataxin, mitochondrial; Friedreich ataxia protein; Fxn

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基因别名: CyaY; FA; FARR; FRDA; FXN; X25

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UniProt ID: (Human) Q16595

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Entrez Gene ID: (Human) 2395

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ferroxidase activity protein binding ferrous iron binding ferric iron binding iron chaperone activity iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding transfer/carrier protein

oxidative phosphorylation heme biosynthetic process ion transport cellular iron ion homeostasis mitochondrion organization adult walking behavior positive regulation of cell proliferation aerobic respiration embryo development ending in birth or egg hatching response to iron ion regulation of ferrochelatase activity protein autoprocessing iron incorporation into metallo-sulfur cluster proprioception positive regulation of cell growth negative regulation of multicellular organism growth negative regulation of apoptotic process positive regulation of catalytic activity small molecule metabolic process negative regulation of organ growth positive regulation of lyase activity cellular response to hydrogen peroxide negative regulation of release of cytochrome c from mitochondria positive regulation of succinate dehydrogenase activity positive regulation of aconitate hydratase activity