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产品信息
PA5-33552
产品规格
种属反应
Bat,
Bovine,
Dog,
Chicken,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human FZD3 / Frizzled 3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550932
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Rabbit, Pig, Opossum, Turkey, Chicken (100%); Xenopus (89%); Platypus, Zebrafish (83%).
For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: frizzled 3; frizzled 3, seven transmembrane spanning receptor; frizzled class receptor 3; frizzled family receptor 3; frizzled homolog 3; Frizzled-3; Fz-3; Fzd3; hFz3; mFz3
基因别名: AU020229; D930050A07Rik; Frizzled-3; FZ-3; Fz3; FZD3
UniProt ID: (Human) Q9NPG1, (Mouse) Q61086
G-protein coupled receptor signaling pathway
nervous system development
non-canonical Wnt signaling pathway
canonical Wnt signaling pathway
establishment of planar polarity
neuron migration
neural tube closure
hair follicle development
positive regulation of neuroblast proliferation
Wnt signaling pathway, calcium modulating pathway
neuron differentiation
cell proliferation in midbrain
post-anal tail morphogenesis
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
inner ear morphogenesis
negative regulation of mitotic cell cycle, embryonic
Wnt signaling pathway, planar cell polarity pathway
sympathetic ganglion development
commissural neuron axon guidance
negative regulation of execution phase of apoptosis
midbrain morphogenesis
signal transduction
cell surface receptor signaling pathway
multicellular organism development
Wnt signaling pathway
midbrain development
brain development
response to drug
response to electrical stimulus
