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Immunogen sequence: HSLFSCEPIT LRMCQDLPYN TTFMPNLLNH YDQQTAALAM EPFHPMVNLD CSRDFRPFLC ALYAPICMEY GRVTLPCRRL CQRAYSECSK LMEMFGVPWP EDMECSRFPD CDEPYPRLVD LNLAGEPTEG APVAVQRDYG FWCPRELKID PDLGYSFLHV RDCSPPCPNM YFRREELSFA RYF; Positive Samples: SH-SY5Y, HeLa, MCF7, Mouse brain, Mouse kidney; Cellular Location: Apical cell membrane, Cell membrane, Cell surface, Membrane, Multi-pass membrane protein
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: frizzled 3; frizzled family receptor 3; frizzled-3; hFz3
Entrez Gene ID: (Rat) 266715