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产品信息
H00007855-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
FZD5 (ENSP00000354607, 1 a.a. approximately 585 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MARPDPSAPP SLLLLLLAQL VGRAAAASKA PVCQEITVPM CRGIGYNLTH MPNQFNHDTQ DEAGLEVHQF WPLVEIQCSP DLRFFLCSMY TPICLPDYHK PLPPCRSVCE RAKAGCSPLM RQYGFAWPER MSCDRLPVLG RDAEVLCMDY NRSEATTAPP RPFPAKPTLP GPPGAPASGG ECPAGGPFVC KCREPFVPIL KESHPLYNKV RTGQVPNCAV PCYQPSFSAD ERTFATFWIG LWSVLCFIST STTVATFLID MERFRYPERP IIFLSACYLC VSLGFLVRLV VGHASVACSR EHNHIHYETT GPALCTIVFL LVYFFGMASS IWWVILSLTW FLAAGMKWGN EAIAGYAQYF HLAAWLIPSV KSITALALSS VDGDPVAGIC YVGNQNLNSL RGFVLGPLVL YLLVGTLFLL AGFVSLFRIR SVIKQGGTKT DKLEKLMIRI GIFTLLYTVP ASIVVACYLY EQHYRESWEA ALTCACPGHD TGQPRAKPEY WVLMLKYFMC LVVGITSGVW IWSGKTVESW RRFTSRCCCR PRRGHKSGGA MAAGDYPEAS AALTGRTGPP GPAATYHKQV SLSHV
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor
基因别名: C2orf31; FZD5; HFZ5
UniProt ID: (Human) Q13467
Entrez Gene ID: (Human) 7855
embryonic axis specification
angiogenesis
positive regulation of T cell cytokine production
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
synapse assembly
negative regulation of cell proliferation
anterior/posterior axis specification, embryo
neuron differentiation
post-embryonic camera-type eye development
positive regulation of interferon-gamma production
T cell differentiation in thymus
non-canonical Wnt signaling pathway
positive regulation of JUN kinase activity
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic camera-type eye morphogenesis
Spemann organizer formation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
apoptotic process involved in morphogenesis
branching involved in labyrinthine layer morphogenesis
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
labyrinthine layer blood vessel development
chorionic trophoblast cell differentiation
regulation of canonical Wnt signaling pathway
cellular response to molecule of bacterial origin
regulation of chorionic trophoblast cell proliferation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
beta-catenin destruction complex disassembly
regulation of bicellular tight junction assembly
