Invitrogen

FZD5 Polyclonal Antibody

View all (10) FZD5 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-88750

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:500
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 130-240 of human FZD5 (NP_0034592)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.03 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805103

Product Specific Information

Immunogen sequence: RMSCDRLPVL GRDAEVLCMD YNRSEATTAP PRPFPAKPTL PGPPGAPASG GECPAGGPFV CKCREPFVPI LKESHPLYNK VRTGQVPNCA VPCYQPSFSA DERTFATFWI G; Positive Samples: Rat kidney; Cellular Location: Cell membrane, Golgi apparatus membrane, Multi-pass membrane protein

Target Information

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor

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Gene Aliases: C2orf31; FZD5; HFZ5

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UniProt ID: (Human) Q13467, (Rat) Q8CHL0

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Entrez Gene ID: (Human) 7855, (Rat) 317674

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Function(s)
beta-amyloid binding G-protein coupled receptor activity protein binding Wnt-protein binding protein kinase binding ubiquitin protein ligase binding Wnt-activated receptor activity transmembrane signal receptor
Process(es)
embryonic axis specification angiogenesis positive regulation of T cell cytokine production G-protein coupled receptor signaling pathway Wnt signaling pathway, calcium modulating pathway synapse assembly negative regulation of cell proliferation anterior/posterior axis specification, embryo neuron differentiation post-embryonic camera-type eye development positive regulation of interferon-gamma production T cell differentiation in thymus non-canonical Wnt signaling pathway positive regulation of JUN kinase activity Wnt signaling pathway involved in dorsal/ventral axis specification positive regulation of transcription from RNA polymerase II promoter cell maturation embryonic camera-type eye morphogenesis Spemann organizer formation canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway apoptotic process involved in morphogenesis branching involved in labyrinthine layer morphogenesis syncytiotrophoblast cell differentiation involved in labyrinthine layer development labyrinthine layer blood vessel development chorionic trophoblast cell differentiation regulation of canonical Wnt signaling pathway cellular response to molecule of bacterial origin regulation of chorionic trophoblast cell proliferation regulation of mitophagy positive regulation of protein targeting to mitochondrion beta-catenin destruction complex disassembly regulation of bicellular tight junction assembly vasculature development multicellular organism development biological_process Wnt signaling pathway embryonic camera-type eye development
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