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FZD5 Antibody (PA5-88750) in IHC (P)
Immunohistochemistry analysis of FZD5 in paraffin-embedded human colon. Samples were incubated with FZD5 Polyclonal antibody (Product # PA5-88750) using a dilution of 1:300 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-88750
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 130-240 of human FZD5 (NP_0034592)
偶联物
形式
Liquid
浓度
0.03 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805103
产品详细信息
Immunogen sequence: RMSCDRLPVL GRDAEVLCMD YNRSEATTAP PRPFPAKPTL PGPPGAPASG GECPAGGPFV CKCREPFVPI LKESHPLYNK VRTGQVPNCA VPCYQPSFSA DERTFATFWI G; Positive Samples: Rat kidney; Cellular Location: Cell membrane, Golgi apparatus membrane, Multi-pass membrane protein
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor
基因别名: C2orf31; FZD5; HFZ5
UniProt ID: (Human) Q13467, (Rat) Q8CHL0
Entrez Gene ID: (Human) 7855, (Rat) 317674
embryonic axis specification
angiogenesis
positive regulation of T cell cytokine production
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
synapse assembly
negative regulation of cell proliferation
anterior/posterior axis specification, embryo
neuron differentiation
post-embryonic camera-type eye development
positive regulation of interferon-gamma production
T cell differentiation in thymus
non-canonical Wnt signaling pathway
positive regulation of JUN kinase activity
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic camera-type eye morphogenesis
Spemann organizer formation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
apoptotic process involved in morphogenesis
branching involved in labyrinthine layer morphogenesis
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
labyrinthine layer blood vessel development
chorionic trophoblast cell differentiation
regulation of canonical Wnt signaling pathway
cellular response to molecule of bacterial origin
regulation of chorionic trophoblast cell proliferation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
beta-catenin destruction complex disassembly
regulation of bicellular tight junction assembly
vasculature development
multicellular organism development
biological_process
Wnt signaling pathway
embryonic camera-type eye development
