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Product Details
MA5-17080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2D12
Immunogen
Purified recombinant fragment of human FZD5 (amino acids:151-217) expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538551
Product Specific Information
MA5-17080 targets FZD5 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17080 immunogen is purified recombinant fragment of human FZD5 (amino acids:151-217) expressed in E. Coli.
MA5-17080 detects FZD5 which has a predicted molecular weight of approximately 64.5kDa.
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434E2135; frizzled 5, seven transmembrane spanning receptor; frizzled family receptor 5; Frizzled-5; Fz-5; Fz5; Fzd-5; FzE5; MGC129692; seven-transmembrane receptor frizzled-5; Wnt receptor
Gene Aliases: C2orf31; FZD5; HFZ5
UniProt ID: (Human) Q13467
Entrez Gene ID: (Human) 7855
embryonic axis specification
angiogenesis
positive regulation of T cell cytokine production
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
synapse assembly
negative regulation of cell proliferation
anterior/posterior axis specification, embryo
neuron differentiation
post-embryonic camera-type eye development
positive regulation of interferon-gamma production
T cell differentiation in thymus
non-canonical Wnt signaling pathway
positive regulation of JUN kinase activity
Wnt signaling pathway involved in dorsal/ventral axis specification
positive regulation of transcription from RNA polymerase II promoter
cell maturation
embryonic camera-type eye morphogenesis
Spemann organizer formation
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
apoptotic process involved in morphogenesis
branching involved in labyrinthine layer morphogenesis
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
labyrinthine layer blood vessel development
chorionic trophoblast cell differentiation
regulation of canonical Wnt signaling pathway
cellular response to molecule of bacterial origin
regulation of chorionic trophoblast cell proliferation
regulation of mitophagy
positive regulation of protein targeting to mitochondrion
beta-catenin destruction complex disassembly
regulation of bicellular tight junction assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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