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Product Details
PA5-33546
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550926
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset (100%).
Target Information
The exact function of the protein encoded by this gene is not known. However, this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus, and a transposase domain at the C-terminus, suggesting that it may belong to the family of DNA-mediated transposons in human.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: frizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; Frizzled-6; Frizzled6; Fz-6; FZD-6; seven transmembrane helix receptor
Gene Aliases: FZ-6; FZ6; FZD6; HFZ6; NDNC10
UniProt ID: (Human) O60353
Entrez Gene ID: (Human) 8323
establishment of planar polarity
neural tube closure
hair follicle development
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
platelet activation
cell proliferation in midbrain
non-canonical Wnt signaling pathway
embryonic nail plate morphogenesis
inner ear morphogenesis
negative regulation of sequence-specific DNA binding transcription factor activity
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
midbrain morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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