Invitrogen

FZD7 Polyclonal Antibody

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FZD7 Antibody (PA1-4137) in WB

Western blot of mouse fz7 in mouse pancreas lysate using Product # PA1-4137.

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产品信息

PA1-4137

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues M(1) R G P G T A A S H S P C(12) of mouse Frizzled.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.02% sodium azide

保存条件

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2109395

产品详细信息

PA1-4137 detects mouse frizzled.

PA1-4137 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~40 kDa protein representing mouse fz in mouse pancreas lysate.

The PA1-4137 immunogen is a synthetic peptide corresponding to residues M(1) R G P G T A A S H S P C(12) of mouse Frizzled. This sequence is 91% conserved in rat.

靶标信息

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

仅用于科研。不用于诊断过程。未经明确授权不得转售。