Invitrogen

FZD8 Polyclonal Antibody

FZD8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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FZD8 Antibody (PA5-33563) in IHC (P)

Immunohistochemistry analysis of FZD8 in human Skin, Melanoma. Samples were incubated with FZD8 polyclonal antibody (Product # PA5-33563). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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产品信息

PA5-33563

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

7-17 µg/mL

产品规格

种属反应

Bovine, Horse, Human, Mouse, Non-human primate, Rat, Xenopus

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic 12 amino acid peptide from N-terminal extracellular domain of human FZD8 / Frizzled 8.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2550943

产品详细信息

Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset, Mouse, Rat, Panda, Bovine, Horse, Opossum, Xenopus (100%).

靶标信息

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。