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产品信息
PA5-95983
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human Fascin/Fascin/FSCN1 (NP_0030791)
偶联物
形式
Liquid
浓度
0.69 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807785
产品详细信息
Immunogen sequence: FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD HAGVLKASAE TVDPASLWEY; Positive Samples: U-251MG, HeLa, NCI-H460, HepG2, SH-SY5Y, Mouse brain, Mouse spinal cord; Cellular Location: Cell junction, Cell projection, Cytoplasm, cytoskeleton, cytosol, filopodium, invadopodium, microvillus
靶标信息
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; Fascin; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; Fascin1; fscn1 {ECO:0000250|UniProtKB:Q16658}; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); Singed-like protein
基因别名: AI663989; FAN1; Fascin; fascin-1; FSCN1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Rat) P85845, (Mouse) Q61553
Entrez Gene ID: (Human) 6624, (Rat) 683788, (Mouse) 14086
cell-cell junction assembly
cell proliferation
anatomical structure morphogenesis
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
cell-cell adhesion
liver development
cellular response to cell-matrix adhesion
actin filament organization
