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Immunogen sequence: QYEDDPHWWF HYLRSQQSTY YDPYDPYPYE TYEPYPYGVD EGPAYTYGSP SPPDPRDCPQ ECDCPPNFPT AMYCDNRNLK YLPFVPSRMK YVYFQNNQIT SIQEGVFDNA TGLLWIALHG NQITSDKVGR KVFSKLRHLE RLYLDHNNLT RMPGPLPRSL RELHLDHNQI SRVPNNALEG LENLTALYLQ HNEIQEVGSS MRGLRSLILL DLSYNHLRKV PDGLPSALEQ LYMEHNNVYT VPDSYFRGAP KLLYVRLSHN SLTNNGLASN TFNSSSLLEL DLSYNQLQKI PPVNTNLENL YLQGNRINEF SISSFCTVVD VVNFSKLQVL RLDGNEIKRS AMPADAPLCL RLASLIEI
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Collagen-binding 59 kDa protein; Fibromodulin; FM; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
基因别名: AI131919; AU041740; FM; FMOD; SLRR2E
UniProt ID: (Human) Q06828, (Mouse) P50608, (Rat) P50609
Entrez Gene ID: (Human) 2331, (Mouse) 14264, (Rat) 64507