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Recommended positive controls: A431, HeLa.
Predicted reactivity: Mouse (96%), Rat (96%), Chicken (80%), Rhesus Monkey (99%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Collagen-binding 59 kDa protein; Fibromodulin; FM; Keratan sulfate proteoglycan fibromodulin; KSPG fibromodulin
基因别名: FM; FMOD; SLRR2E
UniProt ID: (Human) Q06828
Entrez Gene ID: (Human) 2331