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产品信息
PA5-29347
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 168 and 488 of Human Fibulin 3
偶联物
形式
Liquid
浓度
1.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2546823
产品详细信息
Recommended positive controls: 293T, A431, HeLa, HepG2, Mouse liver, Rat liver.
Predicted reactivity: Mouse (97%), Rat (95%), Pig (98%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EGF containing fibulin-like extracellular matrix protein 1; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; FIBL-3; Fibrillin-like protein; Fibulin-3; FLJ35535; MGC111353
基因别名: DHRD; DRAD; EFEMP1; FBLN3; FBNL; FIBL-3; MLVT; MTLV; S1-5
UniProt ID: (Human) Q12805, (Mouse) Q8BPB5
Entrez Gene ID: (Human) 2202, (Mouse) 216616
regulation of transcription, DNA-templated
epidermal growth factor receptor signaling pathway
visual perception
positive regulation of cell proliferation
negative regulation of neuron projection development
peptidyl-tyrosine phosphorylation
positive regulation of cell projection organization
negative regulation of chondrocyte differentiation
camera-type eye development
embryonic eye morphogenesis
post-embryonic eye morphogenesis
regulation of glial cell migration
