Invitrogen

Flotillin 1 Polyclonal Antibody

Flotillin 1 Antibody in Western Blot (WB)

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Flotillin 1 Antibody (PA5-17127) in WB

Western blot was performed using anti-Flotillin 1 Polyclonal Antibody (Product # PA5-17127) and a 47kDa band corresponding to Flotillin 1 was observed across all the cell lines and tissue lysates tested except THP1 which is reported negative for Flotillin 1 expression. Whole cell extracts (30 µg lysate) of Hep G2 (Lane 1), HEK-293 (Lane 2), MCF7 (Lane 3), MDA-MB-231 (Lane 4), HeLa (Lane 5), A549 (Lane 6), THP-1 (Lane 7), tissue extracts of Mouse Lung (Lane 8), Mouse Brain (Lane 9) and Mouse Heart (Lane 10) were electrophoresed using NuPAGE... View More

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产品信息

PA5-17127

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

查看2篇已发表文章 2篇已发表文章

免疫组织化学（悬浮细胞） (IHC (Free))

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Non-human primate, Rat

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding residue surrounding Ile368 of human flotillin-1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

63 µg/mL

纯化类型

Antigen affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

no preservative

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_11000094

产品详细信息

It is not recommended to aliquot this antibody.

靶标信息

Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia.

Journal of extracellular vesicles

Korvenlaita N,Gómez-Budia M,Scoyni F,Pistono C,Giudice L,Eamen S,Loppi S,de Sande AH,Huremagic B,Bouvy-Liivrand M,Heinäniemi M,Kaikkonen MU,Cheng L,Hill AF,Kanninen KM,Jenster GW,van Royen ME,Ramiro L,Montaner J,Batkova T,Mikulik R,Giugno R,Jolkkonen J,Korhonen P,Malm T

Published figure using Flotillin 1 polyclonal antibody (Product # PA5-17127) in Western Blot

Sun Jan 01 00:00:00 UTC 2023

Circulating plasma miR-23b-3p as a biomarker target for idiopathic Parkinson's disease: comparison with small extracellular vesicle miRNA.

Frontiers in neuroscience

Rai S,Bharti PS,Singh R,Rastogi S,Rani K,Sharma V,Gorai PK,Rani N,Verma BK,Reddy TJ,Modi GP,Inampudi KK,Pandey HC,Yadav S,Rajan R,Nikolajeff F,Kumar S

PA5-17127 was used in Western Blot to demonstrate an opposite expression profile of miR-23b-3p in PD and age-matched healthy control in plasma and plasma-derived sEV fractions, where the expression of miR-23b-3p is increased in PD plasma while decreased in plasma-derived sEV fractions.

Sat Dec 02 00:00:00 UTC 2023

Circulating plasma miR-23b-3p as a biomarker target for idiopathic Parkinson's disease: comparison with small extracellular vesicle miRNA.

Frontiers in neuroscience

Rai S,Bharti PS,Singh R,Rastogi S,Rani K,Sharma V,Gorai PK,Rani N,Verma BK,Reddy TJ,Modi GP,Inampudi KK,Pandey HC,Yadav S,Rajan R,Nikolajeff F,Kumar S

Sat Dec 02 00:00:00 UTC 2023

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.

Brain : a journal of neurology

Collin L,Bohrmann B,Göpfert U,Oroszlan-Szovik K,Ozmen L,Grüninger F

PA5-17127 was used in immunohistochemistry - free floating to investigate the mechanisms by which anti-Tau antibodies alleviate Alzheimer's disease in mice