Invitrogen

Folliculin Polyclonal Antibody

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抗体检测数据 (4)

Folliculin Antibody in Immunocytochemistry (ICC/IF)

Folliculin Antibody in Immunocytochemistry (ICC/IF)

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Folliculin Antibody (PA5-120278) in ICC/IF

Immunofluorescence analysis of Folliculin in NIH/3T3 cells. Samples were incubated with Folliculin Polyclonal antibody (Product # PA5-120278) using a dilution of 1:100. Blue: DAPI for nuclear staining.

Folliculin Antibody in Immunocytochemistry (ICC/IF)

Folliculin Antibody in Immunocytochemistry (ICC/IF)

Folliculin Antibody in Immunocytochemistry (ICC/IF)

Folliculin Antibody in Western Blot (WB)

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Folliculin Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence analysis of Folliculin in NIH/3T3 cells. Samples were incubated with Folliculin Polyclonal antibody (Product # PA5-120278) using a dilution of 1:100. Blue: DAPI for nuclear staining.

Folliculin Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence analysis of Folliculin in U2OS cells. Samples were incubated with Folliculin Polyclonal antibody (Product # PA5-120278) using a dilution of 1:100. Blue: DAPI for nuclear staining.

Folliculin Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescence analysis of Folliculin in C6 cells. Samples were incubated with Folliculin Polyclonal antibody (Product # PA5-120278) using a dilution of 1:100. Blue: DAPI for nuclear staining.

Folliculin Antibody in Western Blot (WB) — Western blot analysis of Folliculin in extracts of various cell lines. Samples were incubated with Folliculin Polyclonal antibody (Product # PA5-120278) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

产品信息

PA5-120278

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

免疫细胞化学 (ICC/IF)

1:50-1:200

-

酶联免疫吸附实验 (ELISA)

1 µg/mL

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 341-579 of human FLCN (NP_659434.2).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.62 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2913850

产品详细信息

Positive test controls include: Mouse brain, Mouse thymus, Rat heart. The target is usually found in the following locations: Cytoplasm, Nucleus.

Immunogen sequence: RKLPVFKSLR HMRQVLGAPS FRMLAWHVLM GNQVIWKSRD VDLVQSAFEV LRTMLPVGCV RIIPYSSQYE EAYRCNFLGL SPHVQIPPHV LSSEFAVIVE VHAAARSTLH PVGCEDDQSL SKYEFVVTSG SPVAADRVGP TILNKIEAAL TNQNLSVDVV DQCLVCLKEE WMNKVKVLFK FTKVDSRPKE DTQKLLSILG ASEEDNVKLL KFWMTGLSKT YKSHLMSTVR SPTASESRN

靶标信息

This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: BHD skin lesion fibrofolliculoma protein; Birt-Hogg-Dube syndrome protein; Birt-Hogg-Dube syndrome protein homolog; Folliculin

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基因别名: AU014660; B430214A04Rik; BHD; FLCL; FLCN

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UniProt ID: (Human) Q8NFG4, (Mouse) Q8QZS3, (Rat) Q76JQ2

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Entrez Gene ID: (Human) 201163, (Mouse) 216805, (Rat) 303185

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guanyl-nucleotide exchange factor activity protein binding protein complex binding molecular_function

negative regulation of transcription from RNA polymerase II promoter in utero embryonic development regulation of protein phosphorylation positive regulation of protein phosphorylation cell-cell junction assembly positive regulation of autophagy negative regulation of gene expression negative regulation of mitochondrion organization hemopoiesis negative regulation of cell growth negative regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway TOR signaling regulation of TOR signaling negative regulation of TOR signaling positive regulation of TOR signaling regulation of cytokinesis negative regulation of Rho protein signal transduction regulation of histone acetylation positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of cell adhesion positive regulation of transcription from RNA polymerase II promoter negative regulation of protein kinase B signaling negative regulation of ERK1 and ERK2 cascade negative regulation of protein localization to nucleus negative regulation of cell proliferation involved in kidney development negative regulation of energy homeostasis regulation of pro-B cell differentiation negative regulation of ATP biosynthetic process negative regulation of angiogenesis negative regulation of transcription, DNA-templated negative regulation of cellular respiration negative regulation of mitochondrial DNA metabolic process negative regulation of muscle tissue development negative regulation of post-translational protein modification positive regulation of intrinsic apoptotic signaling pathway biological_process