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产品信息
OSF00008W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from mature mouse Frataxin conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Frataxin.
靶标信息
FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Frataxin, mitochondrial; Friedreich ataxia; Fxn
基因别名: FA; FARR; Frda; Fxn; RGD1565754; X25
UniProt ID: (Mouse) O35943
Entrez Gene ID: (Rat) 499335, (Mouse) 14297
oxidative phosphorylation
heme biosynthetic process
ion transport
cellular iron ion homeostasis
mitochondrion organization
adult walking behavior
positive regulation of cell proliferation
aerobic respiration
embryo development ending in birth or egg hatching
response to iron ion
regulation of ferrochelatase activity
response to organic cyclic compound
iron-sulfur cluster assembly
protein autoprocessing
iron incorporation into metallo-sulfur cluster
proprioception
positive regulation of cell growth
negative regulation of multicellular organism growth
response to drug
negative regulation of apoptotic process
positive regulation of catalytic activity
positive regulation of axon extension
negative regulation of organ growth
positive regulation of transferase activity
positive regulation of lyase activity
positive regulation of oxidoreductase activity
oxidation-reduction process
cellular response to hydrogen peroxide
negative regulation of release of cytochrome c from mitochondria
transport
iron ion homeostasis
