NeoBiotechnologies

Frataxin Monoclonal Antibody (FXN, 2124)

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抗体检测数据 (5)

Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Frataxin Antibody (2395-MSM4-P1ABX) in IHC (P)

Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas using Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX).

Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Frataxin Antibody in Western Blot (WB)

Frataxin Antibody in Peptide array (ARRAY)

Frataxin Antibody in SDS-PAGE (SDS-PAGE)

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Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas using Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX).

Frataxin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreas using Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX).

Frataxin Antibody in Western Blot (WB) — Western Blot analysis of Human Panc-2 and HepG2 cell lysate using Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX).

Frataxin Antibody in Peptide array (ARRAY) — Analysis of Protein Array containing more than 19,000 full-length human proteins Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Frataxin Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE Analyis Purified Frataxin Monoclonal Antibody (Product # 2395-MSM4-P1ABX). Confirmation of Purity and Integrity of Antibody.

产品信息

2395-MSM4-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

-

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

-

肽阵列 (Array)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b, kappa

分类

Monoclonal

类型

Antibody

克隆号

FXN, 2124

抗原

Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

FXN is a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Frataxin, mitochondrial; Friedreich ataxia protein; Fxn

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基因别名: CyaY; FA; FARR; FRDA; FXN; X25

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UniProt ID: (Human) Q16595

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Entrez Gene ID: (Human) 2395

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ferroxidase activity protein binding ferrous iron binding ferric iron binding iron chaperone activity iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding transfer/carrier protein

oxidative phosphorylation heme biosynthetic process ion transport cellular iron ion homeostasis mitochondrion organization adult walking behavior positive regulation of cell proliferation aerobic respiration embryo development ending in birth or egg hatching response to iron ion regulation of ferrochelatase activity protein autoprocessing iron incorporation into metallo-sulfur cluster proprioception positive regulation of cell growth negative regulation of multicellular organism growth negative regulation of apoptotic process positive regulation of catalytic activity small molecule metabolic process negative regulation of organ growth positive regulation of lyase activity cellular response to hydrogen peroxide negative regulation of release of cytochrome c from mitochondria positive regulation of succinate dehydrogenase activity positive regulation of aconitate hydratase activity