Invitrogen

Frizzled-2 Polyclonal Antibody

Frizzled-2 Antibody in Western Blot (WB)

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Frizzled-2 Antibody (38-4700) in WB

Western blot analysis of (A) Caco-2, (B) SK-OV3, (C) HEK293, (D) PC-3, (E) SW480, and (F) HepG2 cell lysates using Rb anti-Frizzled-2 (Product # 38-4700).

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产品信息

38-4700

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

查看2篇已发表文章 2篇已发表文章

免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Human

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide derived from the N-terminal region of human and mouse Frizzled-2 (FZD2).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.1% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2533370

靶标信息

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation.

The Journal of clinical investigation

Weng T,Ko J,Masamha CP,Xia Z,Xiang Y,Chen NY,Molina JG,Collum S,Mertens TC,Luo F,Philip K,Davies J,Huang J,Wilson C,Thandavarayan RA,Bruckner BA,Jyothula SS,Volcik KA,Li L,Han L,Li W,Assassi S,Karmouty-Quintana H,Wagner EJ,Blackburn MR

38-4700 was used in Western Blotting to study the downregulation of CFIm25 in the lungs of patients with idiopathic pulmonary fibrosis and mice with pulmonary fibrosis.