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Product Details
PA5-33543
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Hamster,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550923
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%) Sheep, Rabbit (94%) Opossum (89%).
Target Information
This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dfrizzled2; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 2; frizzled 2, seven transmembrane spanning receptor; frizzled class receptor 2; frizzled family receptor 2; frizzled homolog 2; Frizzled-10; Frizzled-2; Fz-10; Fz-2; FzE2; mFz2; rFz2
Gene Aliases: AL033370; AW456835; Frizzled-2; Fz-10; fz-2; Fz10; Fz2; Fzd10; FZD2; fzE2; hFz2; I79_011598; Mfz10; Mfz10a
UniProt ID: (Human) Q14332, (Rat) Q08464, (Mouse) Q9JIP6
Entrez Gene ID: (Dog) 490937, (Human) 2535, (Horse) 100050809, (Pig) 100337669, (Chinese hamster) 100763109, (Rat) 64512, (Mouse) 57265
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
sensory perception of smell
neuron differentiation
positive regulation of cGMP metabolic process
epithelial cell differentiation
non-canonical Wnt signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
hard palate development
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
inner ear receptor cell development
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
beta-catenin destruction complex disassembly
cell activation
signal transduction
G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
multicellular organism development
ventricular septum morphogenesis
cellular response to vitamin D
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cell surface receptor signaling pathway
Wnt signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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