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GABA(A) alpha 2 Receptor Antibody (AGA-002-200UL) in IHC (F)
Expression of GABRA2 in mouse cerebellum - Immunohistochemical staining of mouse formalin-fixed frozen cerebellum sections with Anti-GABA (A) alpha 2Receptor Antibody (#AGA-002). The receptor subunit is localized mainly on the soma of Purkinje cells. Staining with mouse Anti-parvalbumin (red) suggests thatGABRA2 subunit is restricted to a sub-region of the Purkinje cell.
产品信息
AGA-002-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)TPEPNKKPENKPA, corresponding to amino acid residues 393-405 of rat GABRA2, 2ndintracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 5% sucrose, 1% BSA
内含物
0.025% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ97076; GABA(A) receptor; GABA(A) receptor subunit alpha-2; GABA(A) receptor, alpha 2; GABAAR subunit alpha-2; GABAARalpha2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2; gamma-aminobutyric acid A receptor alpha 2; gamma-aminobutyric acid receptor A2 subunit; Gamma-aminobutyric acid receptor subunit alpha-2
基因别名: C630048P16Rik; Gabra-2; GABRA2
UniProt ID: (Human) P47869, (Mouse) P26048
Entrez Gene ID: (Human) 2555, (Mouse) 14395, (Rat) 289606
