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GABA Transporter 1 (GAT-1) (extracellular) Antibody (AGT-001-200UL) in IHC
Expression of GABATR in rat cerebellum - Immunohistochemical staining of rat cerebellum using Anti-GABA Transporter 1 (GAT-1) (extracellular) Antibody (#AGT-001), (1:200). A. GAT-1 staining is shown in green. B. Neurons expressing gamma amino butyric acid (GABA) were labeled with mouse Anti-parvalbumin (red). C. Merge of the two images demonstrates partial colocalization (arrows). GAT-1 appears both in the ... View More
产品信息
AGT-001-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)ERNMHQMTDGLDK, corresponding to amino acids residues 194-206 of rat GAT-1, 2nd extracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
GAT-1 (SLC6A1) The protein encoded by SLC6A1 is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GABA T-1; GABA T1; GABA transporter 1; GABA transporter protein; GABAT1; gamma-aminobutyric acid (GABA-A) transporter 1; GAT-1; Sodium- and chloride-dependent GABA transporter 1; solute carrier family 6 (neurotransmitter transporter), member 1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
基因别名: A730043E01; GABATHG; GABATR; Gabt; GABT1; GAT-1; GAT1; MAE; SLC6A1; XT-1; Xtrp1
UniProt ID: (Human) P30531, (Rat) P23978, (Mouse) P31648
Entrez Gene ID: (Human) 6529, (Rat) 79212, (Mouse) 232333
transport
neurotransmitter transport
chemical synaptic transmission
learning
response to toxic substance
response to sucrose
response to lead ion
positive regulation of gamma-aminobutyric acid secretion
response to purine-containing compound
gamma-aminobutyric acid transport
negative regulation of synaptic transmission, GABAergic
response to estradiol
response to cocaine
protein homooligomerization
response to calcium ion
gamma-aminobutyric acid import
transmembrane transport
mitophagy in response to mitochondrial depolarization
response to organic substance
response to organonitrogen compound
response to organic cyclic compound
amino acid transmembrane transport
sodium ion transmembrane transport
