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This antibody has been tested in indirect ELISA.
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ36928; G protein-coupled receptor 51; G-protein coupled receptor 51; GABA BR; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABA-B-R2; GABA-BR2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; Gamma-aminobutyric acid type B receptor subunit 2; gb2; HG20; MGC119386; MGC119388; MGC119389; RP23-337N2.1
Gene Aliases: GABABR2; GABBR2; GPR51; GPRC3B; HG20; HRIHFB2099
UniProt ID: (Human) O75899
Entrez Gene ID: (Human) 9568
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