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产品信息
MA5-42479
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JU31-32
抗原
Recombinant protein within C-terminal Human GABA B Receptor 2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2911620
产品详细信息
Positive Control: Rat brain tissue, mouse brain tissue, mouse cerebellum tissue, SH-SY-5Y.
Subcellular Location: Plasma membrane.
靶标信息
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ36928; G protein-coupled receptor 51; G-protein coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABA-B-R2; GABA-BR2; GABABR2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; Gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; HG20; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1
基因别名: GABABR2; GABBR2; Gb2; Gm425; GPR51; GPRC3B; HG20; HRIHFB2099
UniProt ID: (Human) O75899, (Rat) O88871, (Mouse) Q80T41
Entrez Gene ID: (Human) 9568, (Rat) 83633, (Mouse) 242425
