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GAL Antibody (PA5-19206) in IHC (PFA)
Immunohistochemistry (PFA fixed) analysis of GAL using GAL Polyclonal Antibody (Product # PA5-19206) (0.3 µg/mL) in staining of PFA-perfused cryosection of Human Hypothalamus. Antigen retrieval with citrate buffer pH 6 at 80C for 30 min, Cy3-staining. Data obtained by Prof. Erik Hrabovszky, Inst, Exp, Med., Budapest, Hungary.
产品信息
PA5-19206
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (HRSFSDKNGLTSK) corresponding to the internal amino acids of GAL (aa 51-63).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10980348
产品详细信息
This antibody is predicted to react with bovine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
靶标信息
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion. [Uniprot]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Galanin; Galanin message-associated peptide; Galanin peptides; galanin prepropeptide; galanin-message-associated peptide; galanin-related peptide; galanin/GMAP prepropeptide; GMAP; MGC40167
基因别名: ETL8; GAL; GAL-GMAP; GAL1; GALN; GLNN; GMAP
UniProt ID: (Human) P22466, (Rat) P10683, (Mouse) P47212
Entrez Gene ID: (Human) 51083, (Rat) 29141, (Mouse) 14419
inflammatory response
neuropeptide signaling pathway
nervous system development
feeding behavior
protein kinase A signaling
cAMP-mediated signaling
insulin secretion
regulation of glucocorticoid metabolic process
response to insulin
response to immobilization stress
response to drug
positive regulation of apoptotic process
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
negative regulation of lymphocyte proliferation
positive regulation of cortisol secretion
positive regulation of catagen
positive regulation of large conductance calcium-activated potassium channel activity
negative regulation of root hair elongation
negative regulation of cell proliferation
regulation of immune response
