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Recommended positive controls: Galactosylceramidase-transfected 293T.
Predicted reactivity: Dog (87%), Pig (87%), Rhesus Monkey (95%), Bovine (84%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3.2.1.46; beta-galactosidase; Galactocerebrosidase; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase; galactosylceraminidase; GALCERase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A
Gene Aliases: GALC
UniProt ID: (Human) P54803
Entrez Gene ID: (Human) 2581
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