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产品信息
PA5-52852
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2641848
产品详细信息
Immunogen sequence: LIMYSCHGLG GNQYFEYTTQ RDLRHNIAKQ LCLHVSKGAL GLGSCHFTGK NSQVPKDEEW ELAQDQLIRN SGSGTCLTSQ DKKPAMAPCN PSDPHQLWLF V
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.
靶标信息
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.
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生物信息学
蛋白别名: GalNAc transferase 6; GalNAc-T6; Polypeptide GalNAc transferase 6; Polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase; pp-GaNTase 6; Protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
基因别名: GALNAC-T6; GalNAcT6; GALNT6
UniProt ID: (Human) Q8NCL4
Entrez Gene ID: (Human) 11226
