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Immunogen sequence: DDPSPLSRMR EDRDVNDPMP NRGGNGLAPG EDRFKPVVPW PHVEGVEVDL ESIRRINKAK NEQEHHAGG
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
This gene encodes GalNAc transferase 7, a member of the GalNAc-transferase family. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. Unlike other family members, this enzyme shows exclusive specificity for partially GalNAc-glycosylated acceptor substrates and shows no activity with non-glycosylated peptides. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GalNAc-T7; N-acetylgalactosaminyltransferase 7; Polypeptide GalNAc transferase 7; pp-GaNTase 7; Protein-UDP acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
基因别名: GALNAC-T7; GalNAcT7; GALNT7
UniProt ID: (Human) Q86SF2
Entrez Gene ID: (Human) 51809