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GAMT Antibody (PA5-85672) in IHC (P)
GAMT Polyclonal Antibody detects GAMT protein at cytoplasm in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. GAMT Polyclonal Antibody (Product # PA5-85672) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-85672
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human GAMT.
Conjugate
Form
Liquid
Concentration
1.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792811
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (84%), Xenopus laevis (86%), Rhesus Monkey (98%), Bovine (93%).
Positive Control: 293T, Huh7, HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 20; Guanidinoacetate N-methyltransferase
Gene Aliases: AA571402; CCDS2; GAMT; HEL-S-20; PIG2; Spintz1; TP53I2
UniProt ID: (Human) Q14353, (Mouse) O35969
Entrez Gene ID: (Human) 2593, (Mouse) 14431
Performance Guarantee
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